“MUST READ”
tags: weeklylinks
cancer
- Now Wartman is participating in an effort that could make DNA sequencing accessible to many more cancer patients. The Genome Institute at Wash. U. is one of 14 big-name cancer centers partnering with IBM IBM +0.83% to use the computing giant’s Watson artificial intelligence system to compare patients’ genetic data with databases of cancer genes and every scientific paper published about cancer genetics. What takes a team of experts hours or days can be accomplished in minutes. (Read a blog post Wartman wrote about the project here.)
tags: weeklylinks
culture
- n the cell culture practice, heat inactivation of serum products has always been accepted and is one of the basic protocols passed on to new cell culturists. There is no strict standard protocol for heat inactivation, some say incubate at 56 °C for 30 minutes, while some say it can be efficiently performed using temperatures ranging from 45-62 °C and incubation times of 15-60 minutes
What ever way it is done, many
people believe strongly that it is a necessary step to keep your cells happy.
However, these protocols originated before the 1970’s when there were still
technical flaws in the collection, processing, and understanding of serum
More recent practices suggest
that heat inactivation of serum may not be all that necessary.
tags: weeklylinks
- Every step of an experiment, from set-up to collecting, processing, and running assays, requires dozens of steps, all of which are potential sources of variation. In thinking about at an experiment holistically, consistency is key to minimizing variation. When you repeat an experiment, doing everything exactly the same as the first time is crucial.
tags: weeklylinks
- Linking a human DNA sample to a database of human DNA 'fingerprints' is the basis for forensic genetics, which is now a decades-old field. We've shown that the same sort of linking is possible using DNA sequences from microbes inhabiting the human body—no human DNA required,” said Eric Franzosa, Ph.D., a research fellow in the Department of Biostatistics at Harvard Chan. “This opens the door to connecting human microbiome samples between databases, which has the potential to expose sensitive subject information—for example, a sexually-transmitted infection, detectable from the microbiome sample itself."
tags: weeklylinks
- Seattle experts in computer science and immunology are rallying around a new spinoff company from the Fred Hutchinson Cancer Research Center.
Seattle-based Adaptive TCR has nailed down a $4.5 million round of angel investment to
get up and running, Xconomy has learned. The basic concept is to provide
scientists with a high-speed, high-resolution look into the vast diversity of
T-cells of the adaptive immune system that we all produce to ward off
infections, and which sometimes go awry and cause disease.
tags: weeklylinks
- The idea of modifying genes is heralded by some as holding the potential for new therapies addressing rare, genetic diseases, or producing agricultural products with certain desirable characteristics. Precision BioSciences believes that its technology can beat out other emerging gene-editing technologies and it has closed on $25.6 million to prove it.
tags: weeklylinks
nytimes
- Manicurists are routinely underpaid and exploited, and endure ethnic bias and other abuse, The New York Times has found.
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