Monday, September 19, 2016

Weekly Links September 19 , 2016



“MUST READ”
    • For Wiedenheft, the key to survival has been seclusion. When he struck out from Doudna's lab, he opted for a return to Montana State University in Bozeman, where he did his PhD, over an offer from a larger, better-known institution. “At the end of the day, the opportunities for solitude and being outdoors make me more creative and a better scientist,” he says. But like other young scientists who graduate from powerhouse labs, he can't help but wonder how different life might have been if accolades in biomedical science were given to the first authors on a paper, rather than the last. Now and then, he admits, he doesn't feel quite appreciated enough. “Some days it matters, some days it doesn't.”
DISRUPTION, REVOLUTION
    • By this point, you can’t have escaped hearing about CRISPR. First discovered in the 1980’s, the repeated sequences and their function in bacterial defense systems remained a mystery until almost 10 years ago, when it was hailed as the biggest scientific discovery of the century. Since then, scientists have leveraged the adaptable, heritable mechanism to develop the most powerful gene-editing technology to date, known as CRISPR-Cas9.
TOOLS/TECHNIQUES
    • ust as no one in the 80s believed that computers would one day govern every aspect of our lives, today most of us still don’t believe that gene editing will change very much.
This new video from Kurzgesagt – In a Nushell takes a look at the history of genetic engineering, the advent of CRISPR, and how this will impact the future. 
    • Routine PCR? Let’s be honest, there’s no such thing. Even with the simplest PCR reaction things can go wrong, so you need to have a good checklist of ideas for PCR troubleshooting and rectifying the problem. Today I have brainstormed all of the ways I can think of to approach problems with standard PCR reactions.
  • What is CRISPR? - YouTube

HEALTH/MEDECINE
    • Much research efforts are being put into studying the gut microbiome right now because we realize it is super important. In both the inflammatory bowel diseases (IBDs) and in Clostridium difficile infections, the right mirobiome plays a crucial role in recovery. This article will focus on the gut because there are some awesome examples of modern medicine at work. Let’s first take a brief overview of the microbiome in the gut.

COMPANIES
Life Sciences Marketplace Quartzy Raises $17 Million To Build Up The Supply Side Quartzy, a lab supplies marketplace, announced it has closed a $17 million round in Series B financing to help the startup build up the supply of lab equipment offered …
    • Work on a new £60 million facility at Granta Park – set to employ up to 500 staff – could begin late this week or early next, Business Weekly can disclose.
SOMETHING DIFFERENT
    • Yet all of this exposes G.E. to new competition beyond its traditional rivals like Rockwell Automation, Siemens and United Technologies. Tech giants, including Amazon, Cisco, Google, IBM and Microsoft also have their eye on the industrial internet market, as do a bevy of start-ups.
There is precedent for trouble in other industries, of course. Google and Facebook transformed media and advertising, Amazon redefined retailing, and Uber applied an entirely new business model to taxis, which hadn’t changed much in generations.
    • How Yvon Chouinard turned his eco-conscious, anti-corporate ideals into the credo of a successful clothing company.
·         Posted from Diigo. The rest of my favorite links are here.

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