Monday, December 12, 2016

Weekly Links December 12 , 2016



DISRUPTION, REVOLUTION
The adoption of genetic services is key to our ability to provide personalized medicine in the future. The goal is to better diagnose diseases, predict their outcome, and choose the best possible care option for a patient. We still have a long way t…
We have come a long way since next-generation sequencing (NGS) evolved as a set of technologies in the 1970s. The higher throughput and rapid reduction of costs associated with NGS have lead to the accelerated adoption of clinical testing that we ar…
TOOLS/TECHNIQUES
An anti-cancer drug or antibody drug conjugate screening assay is the first step to establish the utility of a drug candidate in killing cancer cells. Nevertheless, these assays are time consuming and tedious. via Pocket
Humans have about 25,000 genes. About 20,000 of these genes are protein-coding genes.1 That means, of course, that humans make at least 20,000 proteins. Not all of them are different since the number of protein-coding genes includes many duplicated …
HEALTH/MEDECINE
That unusual inheritance makes the Y relatively easy to study. If a man acquires a new mutation on a Y chromosome, all his male descendants will inherit it. They can quickly identify themselves as cousins by the mutations that they share. It turns o…
BETHESDA, Md. — The young surgeon was mystified. A fist-size tumor had been removed from the stomach of his patient 12 years earlier, but his doctors had not been able to cut out many smaller growths in his liver. via Pocket
COMPANIES
    • Philippe highlighted that “Europe is good at starting companies, but not at making them world leaders“. Fast-growing tech companies, including biotech, are the fuel of economic growth: “Biotech is open to anyone that has anything interesting to say“. He reckons that Europe will have to contend in the next 20-30 years with China, which is emerging as the next big player.
SOMETHING DIFFERENT
    • With not only jobs but entire industries disappearing, we must help people to retrain for a new world and support them financially while they do so. If communities and economies cannot cope with current levels of migration, we must do more to encourage global development, as that is the only way that the migratory millions will be persuaded to seek their future at home
We can do this, I am an enormous optimist for my species; but it will require the elites, from London to Harvard, from Cambridge to Hollywood, to learn the lessons of the past year. To learn above all a measure of humility.
    • Station F (formerly known as la Halle Freyssinet) is quite an ambitious project and is bound to change the face of the tech ecosystem in Paris. Financed by Xavier Niel and directed by Roxanne Varza, Station F is going be the world’s biggest startup campus with companies like Facebook and TechShop opening offices there
“We’re talking about a startup campus because we’re actually very similar to a university campus,” Varza said. “We’re expecting about one thousand startups in this space.”

Friday, December 9, 2016

Weekly Links December 9 , 2016



“MUST READ”
It is unfortunate that so many journalists begin with a narrative and then back fill the facts and points necessary to tell their narrative. via Pocket
TOOLS/TECHNIQUES
Say you’ve inherited a rare genetic mutation that guarantees you’ll get a certain form of cancer by the time you reach 50 years of age. And that this is most likely how you are going to die. via Pocket
The next generation has arrived, and with it, a clash of titans: Illumina, Thermo Fisher and Qiagen are all competing for the clinical market. Next-generation sequencing (NGS) companies are redefining DNA sequencing. via Pocket
HEALTH/MEDECINE
The objective of the French biotechnology company, Vect-Horus, is to leverage its technology, VECTrans, to facilitate the delivery of drugs into the brain and other organs. via Pocket
COMPANIES
Benchling, a biotech company out of Y Combinator providing cloud-based software for researchers, tells TechCrunch it has raised $7 million in growth funding to continue creating tools to help the science community access research from big pharma and…
Zymergen, a Bay Area startup creating all sorts of materials from genetically altered microbes, just raised $130 million in Series B funding from Softbank. For those unfamiliar, the company makes crazy new materials out of genetically altered microb…
SOMETHING DIFFERENT
As work itself is changing, some of the basic tenets of leadership development are being challenged. The very idea of leading people in jobs is changing with the democratization of work and the continued advance of digital technology. via Pocket

Monday, December 5, 2016

Weekly Links December 5 , 2016



“MUST READ”
A few years ago Eric Schadt met a woman who had cancer. It was an aggressive form of colon cancer that had come on quickly and metastasized to her liver. via Pocket
TOOLS/TECHNIQUES
The action of CRISPR-Cas9 has been described in a wide variety of different ways in the media. via Pocket
I speak biology fluently, but the molecular complexities of the novel genome-editing tool called CRISPR left me as befuddled as when I peruse descriptions of the inflationary universe. via Pocket
How do you pick which antibody you should use in your assay? If you’re starting a new assay and need an antibody for the job, or if your assay isn’t working and you suspect that your antibody could be at fault, then selecting a new antibody from the…
HEALTH/MEDECINE
troubling are the prices of biologics. There is no doubt that these drugs are expensive to conceive, trial and manufacture, compared with traditional small-molecule drugs. But with strong patent monopolies and weak competition after patent expiry, brand biologics are the drug industry's gift that keeps on giving. An analysis of the top-selling drugs worldwide shows how the rise of biologics has reshaped drug salestags: IFTTT Pocket weeklylinks
It was a good day for UniQure, a Dutch biotech company at work on gene therapies for rare diseases. A big pharma company had just made a billion-dollar investment in its future. Or so the headlines blared. via Pocket
COMPANIES
Today, my wife Michelle and I are announcing a $20 million commitment to support the work of the Chan Zuckerberg Biohub, a new laboratory space in San Francisco where researchers and clinical scientists from Stanford, UCSF, and UC Berkeley wi…
The MIT Media Lab spin-off is applying the principles of behavioral science to call centers around the world to improve customer experiences. Cogito compares the characteristics of a current conversation to those of successful historical calls. Using traits like volume, pauses and speed, Cogito makes recommendations to agents in the form of gentle text nudges.
tags: customer experience weeklylink
La Jolla’s tech startup Edico Genome Inc. has landed a partnership with Amazon Web Services, a subsidiary of Amazon that offers a suite of cloud computing services.
The partnership will allow Edico’s Dragen software to be available on Amazon’s virtual servers, helping the company to ramp up processing power. This allows customers to analyze a genome quickly, harnessing the power of Amazon’s servers so they can forgo physical hardware taking up floorspace.
With an industry worth €3.5Bn, butanediol is an important chemical intermediate. Novamont has recently opened the first industrial plant to produce bio-butanediol from sugars, using engineered E. coli. via Pocket
SOMETHING DIFFERENT
When Leonard Cohen was twenty-five, he was living in London, sitting in cold rooms writing sad poems. He got by on a three-thousand-dollar grant from the Canada Council for the Arts. This was 1960, long before he played the festival at the Isle of W…